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1

Fundamental insights into autosomal dominant polycystic kidney disease from human-based cell models

Weydert, Caroline, Decuypere, Jean-Paul, De Smedt, Humbert, Janssens, Peter, Vennekens, Rudi, Mekahli, Djalila

Journal:

Pediatric Nephrology

Year:

2018

Language:

english

File:

PDF, 1.10 MB

english, 2018

2

A double point mutation at residues Ile14 and Val15 of Bcl-2 uncovers a role for the BH4 domain in both protein stability and function

Monaco, Giovanni, La Rovere, Rita, Karamanou, Spyridoula, Welkenhuyzen, Kirsten, Ivanova, Hristina, Vandermarliere, Elien, Di Martile, Marta, Del Bufalo, Donatella, De Smedt, Humbert, Parys, Jan B., E

Journal:

Year:

2018

Language:

english

File:

PDF, 1.13 MB

english, 2018

3

Pannexins, distant relatives of the connexin family with specific cellular functions?

Catheleyne D'hondt, Raf Ponsaerts, Humbert De Smedt, Geert Bultynck, Bernard Himpens

Journal:

Year:

2009

Language:

english

File:

PDF, 690 KB

english, 2009

4

The IRBIT domain adds new functions to the AHCY family

Benoit Devogelaere, Eva Sammels, Humbert De Smedt

Journal:

Year:

2008

Language:

english

File:

PDF, 234 KB

english, 2008

5

Different pattern of differentiation in two LLC-PK1 Clones

Ludo Van Den Bosch, Humbert De Smedt, Roger Borghgraef

Journal:

Journal of Cellular Physiology

Year:

1989

Language:

english

File:

PDF, 666 KB

english, 1989

6

Regulation of the Na+-dependent and the Na+-independent polyamine transporters in renal epithelial cells (LLC-PK1)

Jan B. Parys, Humbert De Smedt, Ludo van Dan Bosch, Roger Borghgraef, Jan Geuns

Journal:

Journal of Cellular Physiology

Year:

1990

Language:

english

File:

PDF, 1.25 MB

english, 1990

7

The role of calmodulin for inositol 1,4,5-trisphosphate receptor function

Nael Nadif Kasri, Geert Bultynck, Ilse Sienaert, Geert Callewaert, Christophe Erneux, Ludwig Missiaen, Jan B Parys, Humbert De Smedt

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2002

Language:

english

File:

PDF, 296 KB

english, 2002

8

Mechanisms responsible for quantal Ca2+release from inositol trisphosphate-sensitive calcium stores

Jan B. Parys, Ludwig Missiaen, Humbert De Smedt, Ilse Sienaert, Rik Casteels

Journal:

Pflügers Archiv European Journal of Physiology

Year:

1996

Language:

english

File:

PDF, 1.06 MB

english, 1996

9

Effects of the immunosuppressant FK506 on intracellular Ca2+ release and Ca2+ accumulation mechanisms

Geert Bultynck, Patrick De Smet, A. Frederik Weidema, Mark Ver Heyen, Karlien Maes, Geert Callewaert, Ludwig Missiaen, Jan B. Parys, Humbert De Smedt

Journal:

The Journal of Physiology

Year:

2000

Language:

english

File:

PDF, 283 KB

english, 2000

10

Ca2+ release induced by inositol 1,4,5-trisphosphate is a steady-state phenomenon controlled by luminal Ca2+ in permeabilized cells

Missiaen, Ludwig, De Smedt, Humbert, Droogmans, Guy, Casteels, Rik

Journal:

Year:

1992

File:

PDF, 369 KB

1992

11

Regulation of InsP3 receptor activity by neuronal Ca2+-binding proteins

Kasri, Nael Nadif, Holmes, Anthony M, Bultynck, Geert, Parys, Jan B, Bootman, Martin D, Rietdorf, Katja, Missiaen, Ludwig, McDonald, Fraser, Smedt, Humbert De, Conway, Stuart J

Journal:

The EMBO Journal

Year:

2003

Language:

english

File:

PDF, 369 KB

english, 2003

12

IP3 receptor-binding partners in cell-death mechanisms

Santeri Kiviluoto, Haidar Akl, Tim Vervliet, Geert Bultynck, Jan B. Parys, Ludwig Missiaen, Humbert De Smedt

Journal:

Wiley Interdisciplinary Reviews: Membrane Transport and Signaling

Year:

2012

Language:

english

File:

PDF, 290 KB

english, 2012

13

Alternative processing of the gene transcripts encoding a plasma-membrane and a sarco / endoplasmic reticulum Ca2+ pump during differentiation of BC3H1 muscle cells

Sabine De Jaegere, Frank Wuytack, Humbert De Smedt, Ludo Van Den Bosch, Rik Casteels

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1993

Language:

english

File:

PDF, 773 KB

english, 1993

14

Modelling of chemical reactions catalysed by membrane-bound enzymes. Determination and significance of the kinetic constants

Karel P.M. Heirwegh, Jules A.T.P. Meuwissen, Peter Van den Steen, Humbert De Smedt

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology

Year:

1989

Language:

english

File:

PDF, 905 KB

english, 1989

15

2,5-Di-(tert-butyl)-1,4-benzohydroquinone and cyclopiazonic acid decrease the Ca2+ permeability of endoplasmic reticulum

Ludwig Missiaen, Humbert De Smedt, Guy Droogmans, Rik Casteels

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1992

Language:

english

File:

PDF, 284 KB

english, 1992

16

The Ca2+/Mn2+ pumps in the Golgi apparatus

Kurt Van Baelen, Leonard Dode, Jo Vanoevelen, Geert Callewaert, Humbert De Smedt, Ludwig Missiaen, Jan B. Parys, Luc Raeymaekers, Frank Wuytack

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2004

Language:

english

File:

PDF, 325 KB

english, 2004

17

Regulation of inositol 1,4,5-trisphosphate-induced Ca2+ release by reversible phosphorylation and dephosphorylation

Veerle Vanderheyden, Benoit Devogelaere, Ludwig Missiaen, Humbert De Smedt, Geert Bultynck, Jan B. Parys

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2009

Language:

english

File:

PDF, 529 KB

english, 2009

18

The IP3 receptor–mitochondria connection in apoptosis and autophagy

Jean-Paul Decuypere, Giovanni Monaco, Geert Bultynck, Ludwig Missiaen, Humbert De Smedt, Jan B. Parys

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2011

Language:

english

File:

PDF, 833 KB

english, 2011

19

Up-regulation of inositol 1,4,5-trisphosphate receptor type 1 is responsible for a decreased endoplasmic-reticulum Ca2+ content in presenilin double knock-out cells

Nael Nadif Kasri, Sarah L. Kocks, Leen Verbert, Sébastien S. Hébert, Geert Callewaert, Jan B. Parys, Ludwig Missiaen, Humbert De Smedt

Journal:

Year:

2006

Language:

english

File:

PDF, 489 KB

english, 2006

20

The suppressor domain of inositol 1,4,5-trisphosphate receptor plays an essential role in the protection against apoptosis

Karolina Szlufcik, Geert Bultynck, Geert Callewaert, Ludwig Missiaen, Jan B. Parys, Humbert De Smedt

Journal:

Year:

2006

Language:

english

File:

PDF, 517 KB

english, 2006

21

The complex regulatory function of the ligand-binding domain of the inositol 1,4,5-trisphosphate receptor

Benoit Devogelaere, Leen Verbert, Jan B. Parys, Ludwig Missiaen, Humbert De Smedt

Journal:

Year:

2008

Language:

english

File:

PDF, 279 KB

english, 2008

22

Regulation of inositol 1,4,5-trisphosphate receptor type 1 function during oocyte maturation by MPM-2 phosphorylation

Veerle Vanderheyden, Takuya Wakai, Geert Bultynck, Humbert De Smedt, Jan B. Parys, Rafael A. Fissore

Journal:

Year:

2009

Language:

english

File:

PDF, 713 KB

english, 2009

23

Intracellular Ca2+ storage in health and disease: A dynamic equilibrium

Eva Sammels, Jan B. Parys, Ludwig Missiaen, Humbert De Smedt, Geert Bultynck

Journal:

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

24

STIM1, but not STIM2, is required for proper agonist-induced Ca2+ signaling

Jean-Paul Decuypere, Giovanni Monaco, Santeri Kiviluoto, Masatsugu Oh-hora, Tomas Luyten, Humbert De Smedt, Jan B. Parys, Ludwig Missiaen, Geert Bultynck

Journal:

Year:

2010

Language:

english

File:

PDF, 812 KB

english, 2010

25

Pannexin channels in ATP release and beyond: An unexpected rendezvous at the endoplasmic reticulum

Catheleyne D'hondt, Raf Ponsaerts, Humbert De Smedt, Mathieu Vinken, Elke De Vuyst, Marijke De Bock, Nan Wang, Vera Rogiers, Luc Leybaert, Bernard Himpens, Geert Bultynck

Journal:

Cellular Signalling

Year:

2011

Language:

english

File:

PDF, 707 KB

english, 2011

26

Modulation of inositol 1,4,5-trisphosphate binding to the various inositol 1,4,5-trisphosphate receptor isoforms by thimerosal and cyclic ADP-ribose

Sara Vanlingen, Henk Sipma, Patrick De Smet, Geert Callewaert, Ludwig Missiaen, Humbert De Smedt, Jan B. Parys

Journal:

Biochemical Pharmacology

Year:

2001

Language:

english

File:

PDF, 167 KB

english, 2001

27

Synergism between hypotonically induced calcium release and fatty acyl-CoA esters induced calcium release from intracellular stores

Ludwig Missiaen, Humbert De Smedt, Jan B Parys, Henk Sipma, Karlien Maes, Sara Vanlingen, Ilse Sienaert, Willy Van Driessche, Rik Casteels

Journal:

Year:

1997

Language:

english

File:

PDF, 768 KB

english, 1997

28

Distribution of inositol 1,4,5-trisphosphate receptor isoforms, SERCA isoforms and Ca2+ binding proteins in RBLm2H3 rat basophilic leukemia cells

Sara Vanlingen, Jan B. Parys, Ludwig Missiaen, Humbert De Smedt, Frank Wuytack, Rik Casteels

Journal:

Year:

1997

Language:

english

File:

PDF, 1.28 MB

english, 1997

29

Agonist-induced down-regulation of type 1 and type 3 inositol 1,4,5-tris-phosphate receptors in A7r5 and DDT1 MF-2 smooth muscle cells

Henk Sipma, Leo Deelman, Humbert De Smedt, Ludwig Missiaen, Jan B. Parys, Sara Vanlingen, Robert H. Henning, Rik Casteels

Journal:

Year:

1998

Language:

english

File:

PDF, 1.19 MB

english, 1998

30

Calcium signalling through nucleotide receptor P2Y2 in cultured human vascular endothelium

Félix Viana, Humbert De Smedt, Guy Droogmans, Bernd Nilius

Journal:

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

31

STIM1 as a key regulator for Ca2+homeostasis in skeletal-muscle development and function

Santeri Kiviluoto, Jean-Paul Decuypere, Humbert De Smedt, Ludwig Missiaen, Jan B Parys, Geert Bultynck

Journal:

Skeletal Muscle

Year:

2011

Language:

english

File:

PDF, 2.58 MB

english, 2011

32

Effect of High Pressure, Detergents and Phaospholipase on the Break in the Arrhenius Plot of Azotobacter Nitrogenase

Francis CEUTERICK, Jozef PEETERS, Karel HEREMANS, Humbert DE SMEDT, Henri OLBRECHTS

Journal:

Year:

1978

Language:

english

File:

PDF, 599 KB

english, 1978

33

Effect of a Cytosolic Ca2+Concentration Ramp on InsP3-Induced Ca2+Release in A7r5 Smooth-Muscle Cells and in EBTr Cells from Tracheal Mucosa

Ludwig Missiaen, Humbert De Smedt, Jan B. Parys, Rik Casteels

Journal:

Biochemical and Biophysical Research Communications

Year:

1997

Language:

english

File:

PDF, 120 KB

english, 1997

34

Cytosolic Ca2+ Controls the Loading Dependence of IP3-Induced Ca2+ Release

Ludwig Missiaen, Humbert De Smedt, Jan B. Parys, Kristel Van Acker, Patrick De Smet, Geert Callewaert

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 73 KB

english, 1999

35

Expression of Inositol 1,4,5-Trisphosphate Receptors in Mouse Oocytes and Early Embryos: The Type I Isoform Is Upregulated in Oocytes and Downregulated after Fertilization

John Parrington, Sophie Brind, Humbert De Smedt, Ratthi Gangeswaran, F. Anthony Lai, Richard Wojcikiewicz, John Carroll

Journal:

Developmental Biology

Year:

1998

Language:

english

File:

PDF, 1.53 MB

english, 1998

36

Pressure effects on lipid-protein interactions in (Na+ + K+)-ATPase

Humbert De Smedt, Roger Borghgraef, Francis Ceuterick, Karel Heremans

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1979

Language:

english

File:

PDF, 599 KB

english, 1979

37

The effect of lanthanum on alamethicin channels in black lipid bilayers

Heinz Gögelein, Humbert de Smedt, Willy van Driessche, Roger Borghgraef

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1981

Language:

english

File:

PDF, 579 KB

english, 1981

38

Phosphorylated intermediates of (Ca2+ + Mg2+)-ATPase and alkaline phosphatase in renal plasma membranes

Humbert de Smedt, Jan B. Parys, Roger Borghgraef, Frank Wuytack

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1983

Language:

english

File:

PDF, 954 KB

english, 1983

39

Calcium-induced phosphorylations and [125I]calmodulin binding in renal membrane preparations

Humbert De Smedt, Jan B. Parys, Frank Wuytack, Roger Borghgraef

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1984

Language:

english

File:

PDF, 1.13 MB

english, 1984

40

Characteristics of Na+-dependent hexose transport in OK, an established renal epithelial cell line

Ludo Van den Bosch, Humbert De Smedt, Roger Borghgraef

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1989

Language:

english

File:

PDF, 572 KB

english, 1989

41

Ruthenium red and compound 4880 inhibit the smooth-muscle plasma-membrane Ca2+ pump via interaction with associated polyphosphoinositides

Ludwig Missiaen, Humbert De Smedt, Guy Droogmans, Frank Wuytack, Luc Raeymaekers, Rik Casteels

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1990

Language:

english

File:

PDF, 499 KB

english, 1990

42

Development of the Na+-dependent hexose carrier in LLC-PK1 cells is dependent on microtubules

Ludo Van Den Bosch, Humbert De Smedt, Roger Borghgraef

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1990

Language:

english

File:

PDF, 719 KB

english, 1990

43

Uptake characteristics of the InsP3-sensitive and -insensitive Ca2+ pools in porcine aortic smooth-muscle cells: different Ca2+ sensitivity of the Ca2+-uptake mechanism

Ludwig Missiaen, Humbert De Smedt, Guy Droogmans, Ingrid Declerck, Lutgart Plessers, Rik Casteels

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 444 KB

english, 1991

44

Analysis of membrane-bound acceptors: A correction function for non-specific accumulation of poorly water-soluble hydrophobic or amphipathic ligands based on the ligand partition concept

Karel P.M. Heirwegh, Humbert De Smedt, Marc Vermeir

Journal:

Biochemical Pharmacology

Year:

1992

Language:

english

File:

PDF, 554 KB

english, 1992

45

Calmodulin stimulation of renal (Ca2+ + Mg2+)-ATPase

Humbert De Smedt, Jan.B. Parys, Roger Borghgraef, Frank Wuytack

Journal:

Year:

1981

Language:

english

File:

PDF, 207 KB

english, 1981

46

F508del-CFTR increases intracellular Ca2+ signaling that causes enhanced calcium-dependent Cl− conductance in cystic fibrosis

Joana Raquel Martins, Patthara Kongsuphol, Eva Sammels, Shehrazade Dahimène, Fadi AlDehni, Luka Alexander Clarke, Rainer Schreiber, Humbert de Smedt, Margarida D. Amaral, Karl Kunzelmann

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2011

Language:

english

File:

PDF, 1.01 MB

english, 2011

47

Regulation of the phosphorylation of the inositol 1,4,5-trisphosphate receptor by protein kinase C

Elke Vermassen, Rafael A Fissore, Nael Nadif Kasri, Veerle Vanderheyden, Geert Callewaert, Ludwig Missiaen, Jan B Parys, Humbert De Smedt

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 181 KB

english, 2004

48

SPCA1 pumps and Hailey–Hailey disease

Ludwig Missiaen, Luc Raeymaekers, Leonard Dode, Jo Vanoevelen, Kurt Van Baelen, Jan B. Parys, Geert Callewaert, Humbert De Smedt, Siegfried Segaert, Frank Wuytack

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 2.26 MB

english, 2004

49

Binding of IRBIT to the IP3 receptor: Determinants and functional effects

Benoit Devogelaere, Nael Nadif Kasri, Rita Derua, Etienne Waelkens, Geert Callewaert, Ludwig Missiaen, Jan B. Parys, Humbert De Smedt

Journal:

Biochemical and Biophysical Research Communications

Year:

2006

Language:

english

File:

PDF, 309 KB

english, 2006

50

Long-lasting changes in GABA responsiveness in cultured neurons

Joelle N Chabwine, Philip Van Damme, Jan Eggermont, Humbert De Smedt, Ludwig Missiaen, Ludo Van Den Bosch, Jan B Parys, Wim Robberecht, Geert Callewaert

Journal:

Neuroscience Letters

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

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